Chainsaw Man (チェンソーマン)

A young man with scruffy blond hair, sharp yellowish-brown eyes with bags underneath, and sharp teeth. As a young boy, he inherits his father's debt from the yakuza upon his father's death. After meeting the Chainsaw Devil, Pochita, he becomes a Devil Hunter in an attempt to clear his debt. The yakuza kill him, and Pochita becomes his heart, setting a contract with Denji, who is to live his dreams of a normal life.

After this, he can transform into the devil-human hybrid known as Chainsaw Man by pulling the cord on his chest. After meeting Makima, he becomes a Public Safety Devil Hunter, to live in humane conditions, although the public sees him as a hero for his heroic deeds. His initial primary motivation is his attraction to Makima.

After Makima's death, his motivation shifts to using his newfound superhero fame as the Chainsaw Man to attract as many women as possible, especially trying to expose his own identity. Currently he enrolls in high school while taking care of Nayuta, Makima's reincarnation.

The Chainsaw Devil who merged with Denji, and was originally the Chainsaw Man himself prior to meeting Denji.

He has the ability to eat a devil and erase their existence, making him "the Devil that Devils fear most".

He first appears in his dog form, actually a weakened state after a fight with mysterious opponents. His true devil form is a large, darker version of Denji’s hybrid form with four arms.

A Public Safety Devil Hunter working under Makima's squad. He has a contract with the Fox Devil and Curse Devil, allowing him to summon the former's head and use a lethal spike in exchange for his lifespan.

He later makes a contract with the Future Devil, allowing him to see a few seconds into the future. Aki is stoic, mature and dependable, but has a soft center when alone. He grows to greatly care about Denji and Power, despite clashing with them.

Desperate to save Denji and Power from the horrible future the Future Devil warned him about, he makes one last contract with Makima to counter the Gun Devil alongside Angel and the other deceased devil hunters, but is killed during the fight, and becomes the Gun Fiend, which Denji is forced to kill.

The Blood Fiend and a Public Safety Devil Hunter in Makima's squad. Power looks like a young woman with long hair; as a Fiend, she has short red horns protruding from her head.

Power loves violence and is childish, greedy, almost entirely self-motivated, and willing to harm others for her own satisfaction. Power loves her cat, Meowy, at one point willing to sacrifice Denji's life to save him.

She comes to care deeply for Denji and Aki, her first true friends. She is killed by Makima in front of Denji, to break his spirit. Power revives as the Blood Devil from Denji's blood, but is fatally wounded by Makima again. Before dying, Power makes a contract with Denji - in exchange for her blood, Denji is to find the reborn Blood Devil and turn her back into Power, so they may be friends again.

A mysterious woman serving as the head of Public Safety Division 4, who takes Denji as her human pet. Makima is cunning, intelligent and manipulative, controlling Denji by taking advantage of his attraction to her with promises of a relationship, while threatening him with extermination in case of disobedience.

For much of the story, her goals are unknown and her good intentions are ambiguous. She is later revealed to be the Control Devil, which embodies the fear of domination, and a member of the Four Horsemen Devils who seeks to use the Chainsaw Man, to whom she is enamored, to create a world without suffering. To this end, she masterminds the misfortunes befalling Denji over the series.

After being killed by Denji, she is reborn as a young girl called Nayuta and placed in his care to be raised as a better person.